Biobased Medical and Dental Adhesive
Official patent title
Bioadhesive for medical and dental applications
Arabic title: لاصق حيوي للتطبيقات الطبية وطب الأسنان
Invention
Invention
Problem
Tissue adhesives must provide reliable wet adhesion, controlled curing, flexibility, sterility, and biocompatibility without excessive heat, toxicity, or inflammation. Natural mixtures also require compositional and microbiological control.
Why it matters
A safe adhesive could assist closure or stabilization of cuts, tears, fractures, dental tissues, or surgical sites, potentially reducing suturing burden in selected uses.
Approach
The bioadhesive combines cyanoacrylate with moringa and hydrolyzed date-seed starch, plant latex, natural gum, plant hydrogel, glycerin, dye, ethanol, and bone powder; a heating and acid-treatment route prepares the starch fraction.
Who may benefit
Potential beneficiaries include medical-device and dental-material developers, surgical-adhesive researchers, trauma-care laboratories, veterinary-product companies, and biomaterials manufacturers.
Potential value
The formulation combines rapid-bonding cyanoacrylate chemistry with a high biobased starch fraction and selected natural gels, gums, latex, glycerin, pigment, and mineral reinforcement.
Background
Background
Medical and dental adhesives can supplement sutures, stabilize tissues, or bond restorative materials. Cyanoacrylates cure rapidly, but performance and safety depend on monomer choice, degradation products, heat release, flexibility, and tissue response. Starches, plant gums, latexes, and hydrogels can alter rheology and provide renewable content, yet biological sourcing also introduces variability, allergy, contamination, and sterilization concerns. The disclosed formulation mixes these classes with bone powder and animal-derived glycerin and proposes direct application to wounds in bone or muscle.
Technology overview
Technology overview
The adhesive includes 25–45 wt.% starch as 5–25 nm particles, cyanoacrylate, jackfruit latex, Acacia gum, okra and moringa hydrogels, sheep-derived glycerin, beetroot and blueberry dyes, ethanol, and beef bone meal. Claimed properties include 15–35 cSt viscosity, pH 7.25–8.75, and an anthocyanin range. Date seeds and moringa coats are heated at 100–175 °C, treated with concentrated mineral acid, and blended with the remaining components. Claims cover application to cuts, tears, or fractures.
Potential applications
Potential applications
- Research on tissue and wound adhesives.
- Dental bonding-material development.
- Bone and muscle repair studies.
- Veterinary bioadhesive research.
Evidence-supported advantages
Evidence-supported advantages
- Combines cyanoacrylate with renewable starches and plant materials.
- Provides defined viscosity, pH, and particle-size ranges.
- Includes natural rheology modifiers and mineral powder.
- Targets multiple medical and dental tissue uses.
- Provides a preparation route for the starch fraction.
Development stage
Development stage
A composition, preparation route, and proposed wound application are described; quantitative wet adhesion, mechanical performance, sterility, biocompatibility, animal safety and efficacy, and clinical testing were not established. The development stage was not independently verified.
Commercial opportunity
Commercial opportunity
The bioadhesive is an early medical-material concept. Development requires formulation lock, wet bond and burst strength, cure time and exotherm, flexibility and degradation, cytotoxicity, sensitization, irritation, hemocompatibility, sterility, animal wound performance, residual-solvent and acid limits, shelf life, source controls, scalable filling, and regulatory clearance before human application.
Patent classifications
Patent classifications
WIPO IPC
- A61L24/00Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L24/04Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
CPC
- A61L24/046Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L24/043Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L24/0031Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L24/06Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L24/0005Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L24/0094Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L24/08Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L2400/12Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
Inventors
Inventors
- First inventorABM Sharif Hossain
Keywords
Keywords
- bioadhesive
- cyanoacrylate
- date seed starch
- moringa starch
- plant hydrogel
- tissue repair
- dental adhesive
- bone powder
Patent document and drawings
Patent document and drawings
The patent publication is mapped to this record. Patent drawings remain within that publication; no separately cleared public media package has been supplied.