US 12453677 B1Patent grantUnited States

Biobased Dental Restorative Filler

Official patent title

Biobased dental filler and method of preparation thereof

Arabic title: حشوة أسنان حيوية الأساس وطريقة تحضيرها

Invention

Invention

Problem

Dental restorative materials must bond, cure, resist chewing loads, limit shrinkage and wear, remain color stable, and be biocompatible. Natural-source fillers add challenges of compositional variability and contamination control.

Why it matters

A validated biobased filler could diversify dental-material supply and create higher-value uses for agricultural and animal by-products, while preserving clinical performance and safety.

Approach

The filler combines date-, olive-, and moringa-derived nanostarch or nanocellulose with dyes, plant gels and gums, animal-derived glycerin and bone components, an acrylate polymer, and optional calcium, zinc, and plasticizer mixtures.

Who may benefit

Potential beneficiaries include dental-material researchers, restorative-product manufacturers, biomaterials companies, dental schools, and agricultural by-product valorization programs.

Potential value

The disclosure integrates biobased nanoscale reinforcement, plant-derived colorants and adhesives, mineral fractions, and photocurable or thermally curable polymer components in one restorative formulation.

Background

Background

Composite dental fillings typically combine a polymer matrix with inorganic reinforcement and curing chemistry. Clinical success depends on compressive and flexural strength, wear, adhesion, shrinkage, water uptake, color, radiopacity, marginal sealing, and biological safety. Biobased starch and cellulose may offer renewable reinforcement, while bone, shell, calcium, and zinc fractions can add mineral content. However, complex plant- and animal-derived mixtures require standardized sourcing, purification, sterilization, allergen control, and testing against established restorative materials before dental use.

Technology overview

Technology overview

The nanocomposite contains 40–60 wt.% nanocellulose and 30–45 wt.% nanostarch, with claimed particle sizes of 18 nm or less and 16 nm or less. Acid hydrolysis processes date seed, olive seed, moringa coat, sheep jawbone, and fish bone. The material is blended with acrylate, plant adhesives and pigments, glycerin, and optional calcium, zinc, and plasticizer mixtures. A damaged tooth is prepared, filled, and cured thermally or by 10–30 seconds of light at 250–850 mW/cm².

Potential applications

Potential applications

  1. Research on restorative dental fillings.
  2. Biobased dental-composite development.
  3. Photocurable and thermally cured restoration studies.
  4. Valorization of agricultural and animal by-products.

Evidence-supported advantages

Evidence-supported advantages

  1. Uses multiple biobased feedstocks.
  2. Combines nanoscale starch and cellulose reinforcement.
  3. Allows light or thermal curing.
  4. Includes optional calcium and zinc mineral fractions.
  5. Provides claimed particle-size and composition ranges.

Development stage

Development stage

A composition, preparation method, and tooth-filling procedure are described; standardized mechanical, adhesion, wear, shrinkage, biological-safety, sterilization, animal, and clinical performance were not established. The development stage was not independently verified.

Commercial opportunity

Commercial opportunity

The formulation is an early dental-material concept. Commercial progress requires a fixed recipe, ISO-relevant mechanical, wear, shrinkage, bond, water-sorption, color, radiopacity, cytotoxicity, sensitization, and pulp-compatibility tests; sterilization and source controls; residual-acid analysis; shelf life; scalable manufacture; dentist handling studies; and regulatory clearance before patient use.

Patent classifications

Patent classifications

WIPO IPC

  • A61K6/898Preparations for medical, dental or toiletry purposes
  • A61K6/30Preparations for medical, dental or toiletry purposes

CPC

  • A61K6/30Preparations for medical, dental or toiletry purposes
  • A61K6/891Preparations for medical, dental or toiletry purposes
  • A61K6/54Preparations for medical, dental or toiletry purposes
  • A61K6/76Preparations for medical, dental or toiletry purposes
  • A61K6/898Preparations for medical, dental or toiletry purposes

Inventors

Inventors

  • First inventorABM Sharif Hossain
  • InventorFazliny Abdul Rahman
  • InventorMoniruddin Chowdhury

Keywords

Keywords

  • dental filler
  • biobased composite
  • nanostarch
  • nanocellulose
  • photocuring
  • acrylate
  • tooth restoration
  • bone mineral

Patent document and drawings

Patent document and drawings

The patent publication is mapped to this record. Patent drawings remain within that publication; no separately cleared public media package has been supplied.