Bio-Derived Bone and Joint Material
Official patent title
Organic biomaterial for bone and joint replacement
Arabic title: مادة حيوية عضوية لاستبدال العظام والمفاصل
Invention
Invention
Problem
Conventional bone and joint replacement materials may present limitations involving brittleness, difficult removal, heat generation, petroleum-derived constituents, or uncertain biological integration.
Why it matters
A moldable material based partly on renewable biological feedstocks could broaden research into implants, bone fillers, and joint-repair components if safety and performance are established.
Approach
The disclosure combines nano-sized cellulose or starch from plant and animal-derived sources with natural pigments, antioxidants, adhesives, plasticizers, calcium oxide, and optional polymers. The mixture is molded and cured thermally or with light into a proposed bone or joint replacement biomaterial.
Who may benefit
Potential beneficiaries include biomaterials laboratories, orthopedic implant developers, tissue-engineering researchers, veterinary device teams, and manufacturers evaluating bio-derived composite feedstocks.
Potential value
The concept combines several agricultural or animal-derived constituents with moldable binders and curing options in a single proposed replacement-material platform.
Background
Background
Bone cements and replacement materials must provide workable handling, structural support, and compatibility with surrounding tissue. The disclosure identifies drawbacks associated with some conventional formulations, including exothermic curing, brittleness, difficult revision, and reliance on synthetic constituents. It proposes using cellulose, starch, mineral material, pigments, antioxidants, adhesives, and plasticizers obtained from varied biological sources. The supplied evidence describes the formulation concept and preparation route but does not establish mechanical strength, degradation behavior, sterility, biocompatibility, or clinical performance.
Technology overview
Technology overview
Candidate cellulose or starch sources include date seed, durum seed coat, moringa seed, fish bone, sheep jawbone, and olive seed. Acid hydrolysis can produce nano-sized material, which is dried and blended with selected pigments, antioxidants, biological adhesives, starches, glycerin, plasticizer, calcium oxide, and optional PVC or acrylic components. The blend is placed in a mold and photo-cured or thermally cured. The patent defines ingredient alternatives and processing steps rather than a validated implant specification.
Potential applications
Potential applications
- Research prototypes for bone-defect filling materials.
- Candidate molded components for joint-replacement studies.
- Bio-derived composite research for orthopedic devices.
- Material-screening platforms for tissue-engineering laboratories.
Evidence-supported advantages
Evidence-supported advantages
- The formulation can incorporate multiple renewable biological sources.
- Molding and either thermal or photo-curing are contemplated.
- The disclosure offers several natural adhesive and plasticizer alternatives.
- Calcium-containing and optional polymer components can be selected for formulation studies.
Development stage
Development stage
A formulation and molding process is described at patent level; mechanical, biological, in-vivo, sterilization, and clinical validation are not established in the supplied evidence.
Commercial opportunity
Commercial opportunity
The concept may interest orthopedic biomaterial and bio-composite developers, but commercialization requires defined composition, reproducible manufacturing, mechanical and fatigue testing, degradation and extractables studies, sterilization validation, biocompatibility, animal studies, regulatory review, and clinical evidence. No implant safety or performance claim has been independently verified in the supplied record.
Patent classifications
Patent classifications
WIPO IPC
- A61L27/44Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L27/36Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
CPC
- A61L27/3608Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L27/3637Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L27/3691Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L27/446Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L2400/12Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
- A61L2430/02Sterilising materials or objects; disinfecting, sterilising or deodorising air; chemical aspects and materials of bandages, dressings, absorbent pads or surgical articles
Inventors
Inventors
- First inventorABM Sharif Hossain
- InventorMoniruddin Chowdhury
- InventorFazliny Abdul Rahman
Keywords
Keywords
- bone replacement
- joint replacement
- biomaterial
- nanocellulose
- nanostarch
- bio-derived composite
- molding
- curing
Patent document and drawings
Patent document and drawings
The patent publication is mapped to this record. Patent drawings remain within that publication; no separately cleared public media package has been supplied.